Effects of expectation on placebo-induced dopamine release in Parkinson disease.
Identifieur interne : 001A52 ( Main/Exploration ); précédent : 001A51; suivant : 001A53Effects of expectation on placebo-induced dopamine release in Parkinson disease.
Auteurs : Sarah C. Lidstone [Canada] ; Michael Schulzer ; Katherine Dinelle ; Edwin Mak ; Vesna Sossi ; Thomas J. Ruth ; Raul De La Fuente-Fernández ; Anthony G. Phillips ; A Jon StoesslSource :
- Archives of general psychiatry [ 1538-3636 ] ; 2010.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (therapeutic use), Attitude to Health, Basal Ganglia (diagnostic imaging), British Columbia, Clinical Trials as Topic (methods), Dopamine (metabolism), Female, Humans, Levodopa (therapeutic use), Male, Middle Aged, Parkinson Disease (diagnostic imaging), Parkinson Disease (drug therapy), Parkinson Disease (metabolism), Placebo Effect, Placebos, Positron-Emission Tomography, Raclopride, Research Design, Reward.
- MESH :
- chemical , metabolism : Dopamine.
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- diagnostic imaging : Basal Ganglia, Parkinson Disease.
- drug therapy : Parkinson Disease.
- metabolism : Parkinson Disease.
- methods : Clinical Trials as Topic.
- Aged, Attitude to Health, British Columbia, Female, Humans, Male, Middle Aged, Placebo Effect, Placebos, Positron-Emission Tomography, Raclopride, Research Design, Reward.
Abstract
Expectations play a central role in the mechanism of the placebo effect. In Parkinson disease (PD), the placebo effect is associated with release of endogenous dopamine in both nigrostriatal and mesoaccumbens projections, yet the factors that control this dopamine release are undetermined.
DOI: 10.1001/archgenpsychiatry.2010.88
PubMed: 20679593
Affiliations:
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Lidstone</name><affiliation wicri:level="1"><nlm:affiliation>Pacific Parkinson's Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Pacific Parkinson's Research Centre, University of British Columbia, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Schulzer, Michael" sort="Schulzer, Michael" uniqKey="Schulzer M" first="Michael" last="Schulzer">Michael Schulzer</name></author><author><name sortKey="Dinelle, Katherine" sort="Dinelle, Katherine" uniqKey="Dinelle K" first="Katherine" last="Dinelle">Katherine Dinelle</name></author><author><name sortKey="Mak, Edwin" sort="Mak, Edwin" uniqKey="Mak E" first="Edwin" last="Mak">Edwin Mak</name></author><author><name sortKey="Sossi, Vesna" sort="Sossi, Vesna" uniqKey="Sossi V" first="Vesna" last="Sossi">Vesna Sossi</name></author><author><name sortKey="Ruth, Thomas J" sort="Ruth, Thomas J" uniqKey="Ruth T" first="Thomas J" last="Ruth">Thomas J. Ruth</name></author><author><name sortKey="De La Fuente Fernandez, Raul" sort="De La Fuente Fernandez, Raul" uniqKey="De La Fuente Fernandez R" first="Raul" last="De La Fuente-Fernández">Raul De La Fuente-Fernández</name></author><author><name sortKey="Phillips, Anthony G" sort="Phillips, Anthony G" uniqKey="Phillips A" first="Anthony G" last="Phillips">Anthony G. 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Ruth</name></author><author><name sortKey="De La Fuente Fernandez, Raul" sort="De La Fuente Fernandez, Raul" uniqKey="De La Fuente Fernandez R" first="Raul" last="De La Fuente-Fernández">Raul De La Fuente-Fernández</name></author><author><name sortKey="Phillips, Anthony G" sort="Phillips, Anthony G" uniqKey="Phillips A" first="Anthony G" last="Phillips">Anthony G. Phillips</name></author><author><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A Jon" last="Stoessl">A Jon Stoessl</name></author></analytic><series><title level="j">Archives of general psychiatry</title><idno type="eISSN">1538-3636</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Antiparkinson Agents (therapeutic use)</term><term>Attitude to Health</term><term>Basal Ganglia (diagnostic imaging)</term><term>British Columbia</term><term>Clinical Trials as Topic (methods)</term><term>Dopamine (metabolism)</term><term>Female</term><term>Humans</term><term>Levodopa (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (diagnostic imaging)</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (metabolism)</term><term>Placebo Effect</term><term>Placebos</term><term>Positron-Emission Tomography</term><term>Raclopride</term><term>Research Design</term><term>Reward</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Dopamine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term><term>Levodopa</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Basal Ganglia</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Clinical Trials as Topic</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Attitude to Health</term><term>British Columbia</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Placebo Effect</term><term>Placebos</term><term>Positron-Emission Tomography</term><term>Raclopride</term><term>Research Design</term><term>Reward</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Expectations play a central role in the mechanism of the placebo effect. In Parkinson disease (PD), the placebo effect is associated with release of endogenous dopamine in both nigrostriatal and mesoaccumbens projections, yet the factors that control this dopamine release are undetermined.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="De La Fuente Fernandez, Raul" sort="De La Fuente Fernandez, Raul" uniqKey="De La Fuente Fernandez R" first="Raul" last="De La Fuente-Fernández">Raul De La Fuente-Fernández</name><name sortKey="Dinelle, Katherine" sort="Dinelle, Katherine" uniqKey="Dinelle K" first="Katherine" last="Dinelle">Katherine Dinelle</name><name sortKey="Mak, Edwin" sort="Mak, Edwin" uniqKey="Mak E" first="Edwin" last="Mak">Edwin Mak</name><name sortKey="Phillips, Anthony G" sort="Phillips, Anthony G" uniqKey="Phillips A" first="Anthony G" last="Phillips">Anthony G. Phillips</name><name sortKey="Ruth, Thomas J" sort="Ruth, Thomas J" uniqKey="Ruth T" first="Thomas J" last="Ruth">Thomas J. Ruth</name><name sortKey="Schulzer, Michael" sort="Schulzer, Michael" uniqKey="Schulzer M" first="Michael" last="Schulzer">Michael Schulzer</name><name sortKey="Sossi, Vesna" sort="Sossi, Vesna" uniqKey="Sossi V" first="Vesna" last="Sossi">Vesna Sossi</name><name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A Jon" last="Stoessl">A Jon Stoessl</name></noCountry><country name="Canada"><noRegion><name sortKey="Lidstone, Sarah C" sort="Lidstone, Sarah C" uniqKey="Lidstone S" first="Sarah C" last="Lidstone">Sarah C. Lidstone</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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